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Case Study

Localized acquired pseudoxanthoma elasticum after treatment with cream containing Striadril complex


Keywords | Summary | Correspondence | References


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Localized acquired pseudoxanthoma elasticum is a rare disorder which has similar clinical and histopathology characteristics to the inherited form of the disease except the lack of vascular and ocular involvement. Herein a clinical case of a localized acquired cutaneous pseudoxanthoma elasticum after treatment with Striadril complex-containing anti-wrinkle cream is described. The possible causative relationship between the application of the cosmeceutical and the coincidental disease development is discussed.


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Address of Correspondence

Maria Balabanova, MD, PhD
Department of Dermatology and Venereology
Medical Faculty – Sofia
1 St. Georgi Sofiiski Blvd.
1431 Sofia, Bulgaria


In conclusion, we describe a clinical case of a LAPXE coinciding anti-skin aging treatment with Striadril complex-containing cream.


1. Bercovitch L, Terry P (2004) Pseudoxanthoma elasticum. J Am Acad Dermatol 2004; 51: S13-4.
2. Hicks J, Carpenter CL, Jr, Reed RJ (1979) Periumbilical perforating pseudoxanthoma elasticum. Arch Dermatol; 115: 300-3.
3. Nielsen AO, Christensen OB, Hentzer B, Johnson E, Kobayasi T (1978) Salpeter-induced dermal changes electron-microscopically indistinguishable from pseudoxanthoma elasticum. Acta Derm Venereol; 58: 323-7.
4. Robinson LR, Fitzgerald NC, Doughty DG, Dawes NC, Berge CA, Bissett DL (2005) Topical palmitoyl pentapeptide provides improvement in photoaged human facial skin. Int J Cosmet Sci; 27: 155-60.
5. Beer KR (2006) Comparative evaluation of the safety and efficacy of botulinum toxin type A and topical creams for treating moderate-tosevere glabellar rhytids. Dermatol Surg; 32: 184-97.



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